Although it seems that No Way Home will act as a conclusion for Tom Holland's standalone Spider-Man movies, the actor hasn't totally ruled out appearing in a fourth installment. In a new interview with EW, Holland explains that, should a fourth film ever move forward, it would have to be notably different from what they've done with the Homecoming trilogy. The film would have to explore new territory and be tonally different from the films they've done before, says Holland. Read Holland's full comment below:
"I think if we were lucky enough to dive into these characters again, you'd be seeing a very different version. It would no longer be the Homecoming trilogy. We would give it some time and try to build something different and tonally change the films. Whether that happens or not, I don't know. But we were definitely treating [No Way Home] like it was coming to an end, and it felt like it."
It seems like No Way Home will conclusively act as a final installment to the Homecoming era of Spider-Man, but the prospect of a fourth film isn't outside the realm of possibility. Although many standalone MCU films stop on or before the third installment, there are occasional exceptions. Thor: Love and Thunder, for example, the fourth installment in the standalone Thor films, is due out next year. Even Sam Raimi's Spider-Man trilogy had a planned fourth installment at one point.
If Holland does indeed ever return for a fourth Spider-Man film, it would be interesting to see a new angle. Holland noting that they would "give it some time" suggests that, not only would a fourth film need to take some time to put together in the real world, but it could focus on a more grown-up version of Peter Parker. Perhaps Peter is attending university or in the midst of adulthood working at the Daily Bugle as a photographer. While the Homecoming films have been very light and comedic in tone, it would be interesting to see a more mature, or maybe even slightly darker take on Spider-Man. For now, though, it does seem like No Way Home is the last we'll be seeing of Tom Holland's Spider-Man for quite some time. Spider-Man: No Way Home is scheduled to release later this year on December 17th.
Source: EW